Bromination of Substituted Acetones

Ortho-substituted iodobenzenes as novel organocatalysts for bromination of alkenes.

Suitably ortho-substituted iodobenzenes act as organocatalysts for the transfer of electrophilic bromine from N-bromosuccinimide to alkenes via the intermediacy of bromoiodinanes.

An efficient H2O2-based oxidative bromination of alkenes, alkynes, and aromatics by a divanadium-substituted phosphotungstate.

A divanadium-substituted phosphotungstate TBA(4)[γ-HPV(2)W(10)O(40)] (TBA = tetra-n-butylammonium) could act as an effective homogeneous catalyst for the H(2)O(2)-based oxidative bromination.

Dioxane dibromide mediated bromination of substituted coumarins under solvent-free conditions

An efficient solvent-free protocol for regioselective bromination of substituted coumarins has been developed by using dioxane dibromide as the solid brominating agent. The efficacy of the solvent-free protocol has been established. The effects of the electronic nature and location of the substituents on the outcome of the reaction have been rationalized with a proposed mechanism.

Acute toxicity of some perhalogenated acetones.

Bromination of Alkenes

The two most common halogenation reactions are chlorination and bromination. The addition of these halogens to alkenes yields 1,2-dihalides. Chlorinations reactions are used to synthesize over 6 million tons per year of ethylene dichloride (1,2-dichloroethane) for use as a solvent and for subsequent polymerization to produce poly(vinylchloride) known more commonly as PVC which is used for plumb...